Anti-ageing drugs could make more organs viable for transplants

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Surgeons finishing up a kidney transplant

Christopher Furlong/Getty Photographs

Medication that clear away worn-out cells might enhance the success of transplanted organs from older donors, in line with analysis in mice.

As we grow old, some cells cease dividing, however linger as an alternative of dying off. These so-called senescent cells accumulate in our organs, releasing chemical substances that may set off irritation and promote illness.

When an organ from an older donor is transplanted right into a youthful particular person, senescent cells within the transplanted organ can activate senescence within the recipient’s personal cells. This “switch” of ageing can worsen …


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